Professor CHAN Ka Leung
Personal Information
Position and Department
- Professor of Medicine and Therapeutics (Clinical), Department of Medicine and Therapeutics
ORCiD0000-0001-7388-2436
CUHK Research Outputs
- Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns (2022)
- Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (2021)
- Colorectal Cancer Screening Based on Age and Gender A Cost-Effectiveness Analysis (2016)
- Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection (2016)
- Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers (2016)
- Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development (2016)
- Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer (2016)
- Questionnaire-Based Survey on Diagnostic and Therapeutic Endoscopies and H. pylori Eradication for Elderly Patients in East Asian Countries (2016)
- Risk of Advanced Adenomas in Siblings of Individuals With Advanced Adenomas: A Cross-Sectional Study (2016)
- Screening strategies for colorectal cancer among patients with nonalcoholic fatty liver disease and family history (2016)
- Systematic review with meta-analysis: faecal occult blood tests show lower colorectal cancer detection rates in the proximal colon in colonoscopy-verified diagnostic studies (2016)
- Validation of a risk prediction score for proximal neoplasia in colorectal cancer screening: a prospective colonoscopy study (2016)
- Association between serrated polyps and the risk of synchronous advanced colorectal neoplasia in average-risk individuals (2015)
- Autophagy Mediates HBx-Induced Nuclear Factor-kappa B Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes (2015)
- Higher Estimated Net Endogenous Acid Production May Be Associated with Increased Prevalence of Nonalcoholic Fatty Liver Disease in Chinese Adults in Hong Kong (2015)
- Identification of subjects at risk of proximal advanced neoplasia for colorectal cancer screening (2015)
- Prevention of gastrointestinal events in patients on antithrombotic therapy in the peri-endoscopy period: Review of new evidence and recommendations from recent guidelines (2015)
- Regret on Choice of Colorectal Cancer Screening Modality Was Associated with Poorer Screening Compliance: A 4-Year Prospective Cohort Study (2015)
- Effects of Intravenous and Oral Esomeprazole in the Prevention of Recurrent Bleeding from Peptic Ulcers after Endoscopic Therapy (2014)
- microRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma (2014)
- Oncogenic induction of cellular high CpG methylation by Epstein-Barr virus in malignant epithelial cells (2014)
- Pharmacologic Options in the Management of Upper Gastrointestinal Bleeding: Focus on the Elderly (2014)
- Proton Pump Inhibitors and Nonsteroidal Anti-inflammatory Drug-Related Lower Gastrointestinal Adverse Events (2014)
- Systematic review with meta-analysis: Accuracy of interferon-gamma releasing assay and anti-Saccharomyces cerevisiae antibody in differentiating intestinal tuberculosis from Crohn's disease in Asians (2014)
- The Janus Face of Cathelicidin in Tumorigenesis (2014)
- A novel crosstalk between two major protein degradation systems Regulation of proteasomal activity by autophagy (2013)
- Capsule endoscopy in acute upper gastrointestinal hemorrhage: a prospective cohort study (2013)
- Challenges in the management of acute peptic ulcer bleeding (2013)
- Commentary: improving the use of gastroprotective agents among high-risk NSAID users authors' reply (2013)
- Commentary: natural history and management of acute upper GI bleeding due to tumours (2013)
- Community-based lifestyle modification programme for non-alcoholic fatty liver disease: A randomized controlled trial (2013)
- Diagnostic accuracy of faecal immunochemical test for screening individuals with a family history of colorectal cancer (2013)
- Dysregulation and crosstalk of cellular signaling pathways in colon carcinogenesis (2013)
- Effect of amlodipine on platelet inhibition by clopidogrel in patients with ischaemic heart disease: a randomised, controlled trial (2013)
- Effect of probiotic bacteria on the intestinal microbiota in irritable bowel syndrome (2013)
- Effects of Helicobacter pylori Infection on Long-term Risk of Peptic Ulcer Bleeding in Low-Dose Aspirin Users (2013)
- Endoscopic Therapy as an Alternative to Radical Surgery for Early Stage Esophageal Adenocarcinoma With Submucosal Invasion? (2013)
- Epigenetic-mediated tumor suppressor genes as diagnostic or prognostic biomarkers in gastric cancer (2013)
- Genome-wide association and sequencing studies on colorectal cancer (2013)
- Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study (2013)
- Infections and inflammatory bowel disease: Challenges in Asia (2013)
- Letter: dyspepsia, anxiety and depression Reply (2013)
- Mechanisms Behind the Increased Vulnerability of the Aging Stomach to NSAID-Related Injury: Perhaps Not As Simple As We May Think (2013)
- Peroral endoscopic myotomy for treatment of achalasia: from bench to bedside (2013)
- Prospective cohort study of compliance with faecal immunochemical tests for colorectal cancer screening in Hong Kong (2013)
- Randomized Trial of Endoscopic Sphincterotomy With Balloon Dilation Versus Endoscopic Sphincterotomy Alone for Removal of Bile Duct Stones (2013)
- Statements of the Malaysian Society of Gastroenterology & Hepatology and the National Heart Association of Malaysia task force 2012 working party on the use of antiplatelet therapy and proton pump inhibitors in the prevention of gastrointestinal bleeding (2013)
- The Knowledge of Colorectal Cancer Symptoms and Risk Factors among 10,078 Screening Participants: Are High Risk Individuals More Knowledgeable? (2013)
- The use of prophylactic gastroprotective therapy in patients with nonsteroidal anti-inflammatory drug- and aspirin-associated ulcer bleeding: a cross-sectional study (2013)
- Tumor Suppressor Functions of miR-133a in Colorectal Cancer (2013)
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